Combiflam Tablet: uses, dose, side effects, price & composition

Combiflam Tablet

Combiflam (325/400 mg) Tablet may be a combination medicine wont to relieve pain related to menstrual cycles and arthritis. it's wont to relieve mild to moderate pain related to a headache, toothache, muscle pain, or back pain. it's also wont to temporarily relieve fever. This medicine should be used with caution thanks to the increased risk of liver damage and bleeding complications.

Side effects

Major & minor side effects for Combiflam (325/400 mg) Tablet

• Nausea or Vomiting
• Rash
• Gastric / Mouth Ulcer
• Bloody and cloudy urine
• Abnormal blood counts
• Fatigue
• Heartburn
• Abdominal discomfort
• Constipation
• Decreased urine output
• Yellow colored eyes or skin
• Ringing or buzzing within the ears
• Loss of appetite
• Drowsiness
• Vomiting of blood

Uses of Combiflam (325/400 mg) Tablet

What is it prescribed for?

• Fever and Pain
• Mild to Moderate pain
• Menstrual Cramps
• Osteoarthritis
• Rheumatoid Arthritis
• Gout

When to not use?

• Allergy

This medicine isn't recommended to be used in patients with a known allergy to paracetamol, ibuprofen, or the other NSAIDs.

• Analgesic Nephropathy (Kidney Disease)

This medicine isn't recommended to be used in patients affected by an impaired kidney function related to excessive use of painkillers.

• Severe liver impairment

This medicine isn't recommended to be used in patients with severe liver impairment thanks to the increased risk of great adverse effects.

• Asthma

This medicine isn't recommended to be used in patients with a known history of NSAID-induced asthma thanks to the increased risk of worsening of the patient's condition.

• Coronary Artery Bypass Surgery (CABG)

This medicine isn't recommended to be used in patients with a recent operation thanks to the increased risk of severe adverse reactions.

• Peptic Ulcer

This medicine isn't recommended to be used in patients with peptic ulceration disease or any gastrointestinal bleeding disorders thanks to the increased risk of worsening of the patient's condition.

• Pediatric patients

This medicine isn't recommended to be used in children.

Combiflame

Warnings

Warnings for special population

• Pregnancy

This medicine isn't recommended to be used in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

• Breast-feeding

This medicine isn't recommended to be used in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

General warnings

• Chronic Malnutrition

This medicine should be used with extreme caution in patients affected by malnourishment thanks to the increased risk of severe adverse effects. Appropriate dose adjustments or replacement with an appropriate alternative could also be required in some cases supported the clinical condition.

• Gastro-intestinal bleeding

This medicine may cause severe gastrointestinal bleeding and perforation after prolonged usage. These adverse events may occur with or all of sudden symptoms. This risk is particularly higher within the elderly population and in patients with a history of gastrointestinal diseases. Appropriate dose adjustments or replacement with an appropriate alternative could also be required supported the clinical condition.

• Chronic alcoholics

This medicine isn't recommended to be used in chronic alcoholic patients thanks to the increased risk of severe liver damage.

• Anemia

This medicine should be used with caution in patients with anemia thanks to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with an appropriate alternative could also be necessary supported the clinical condition.

• Liver impairment

This medicine should be used with extreme caution in patients affected by liver function impairment or active liver diseases thanks to the increased risk of severe adverse effects. Close monitoring of liver function is important while receiving this medicine. Appropriate dose adjustments or replacement with an appropriate alternative could also be required in some cases supported the clinical condition.

Dosage

• Missed Dose

If a dose of this medicine is missed, take the dose as soon as you commit it to memory . If it's almost time for subsequent dose, skip the missed dose and take subsequent dose. don't double the dose to form up for the missed one.

• Overdose

Seek emergency medical treatment or contact the doctor just in case of an overdose.

Interactions

All drugs interact differently for person to person. you ought to check all the possible interactions together with your doctor before starting any medicine.

Interaction with Alcohol

• Description

N/A

• Instructions

Consumption of alcohol isn't recommended during treatment with this medicine thanks to the increased risk of great side effects like severe gastrointestinal bleeding, dizziness, fatigue, weakness, rashes, nausea, joint pain, fever, etc.

Interaction with Medicine

• Carbamazepine
• Methotrexate
• Phenytoin
• Sodium Nitrite
• Leflunomide
• Prilocaine
• Corticosteroids
• Aspirin
• Antihypertensives
• Anticoagulants

Disease interactions

• Fluid Retention and edema

This medicine may cause fluid retention and edema in some patients. Close monitoring of vital sign , electrolyte levels, and heart function could also be required supported the clinical condition. Appropriate dose adjustments or replacement with an appropriate alternative could also be necessary in some cases.

• Skin rash

This medicine may cause fatal skin allergies with none warnings in some patients. Signs and symptoms like rashes, hives, fever, or other allergic symptoms should be reported to the doctor with none delay. Appropriate corrective measures, dose adjustments, or replacement with an appropriate alternative could also be required supported the clinical condition.

Food interactions

Information not available.

Lab interactions

• 5-HIAA Urine Test

You may get a false-positive result for this test while taking this medicine. it's advised that you simply inform the doctor and lab technician about all of your current medicines including herbs and supplements before undergoing any lab tests.

This is not an exhaustive list of possible drug interactions. you ought to consult your doctor about all the possible interactions of the drugs you’re taking.

General Instructions

Take this medicine exactly as prescribed by the doctor. don't absorb larger or smaller quantities than recommended. This medicine should be crazy food or immediately after food. Consult the doctor if you experience any undesirable side effects. make sure that the treatment course is completed. don't stop the utilization of this medicine without consulting your doctor.

Disease during which Combiflam Tablet Should be Avoided:

The Combiflam Tablet might affect this disease or conditions and intensify it. Thereby, it's suggested to share all the medical record with a doctor.

Some of the diseases and conditions that Combiflam is understood to accentuate is mentioned below:

• Asthma (Major) - Combiflam should be avoided within the case of NSAID-sensitive asthma. If there existed any trace of NSAID-sensitive asthma within the past, a doctor must be told about it. it's advisable to travel for substitute of Combiflam, after consulting doctor.
• Fluid retention and Edema (Major)- If a private has the priority of fluid retention and edema, one must consult a medical professional before the consumption of the drugs . Also, during the course of drugs , heart conditions and vital sign should be monitored on the regular basis.
• Skin rash (Major) - There are cases of Combiflam causing skin allergies like hives, rashes, fever or other allergy with none prior warning. If a private experience any of this type of skin allergy, a doctor should be consulted as soon as possible, because the condition requires immediate medical intervention.
• Liver disease- the drugs should be avoided by patients affected by any quite disease because the medicine may intensify the consequences . it's recommended to watch the liver functions while consuming the Combiflam. it's advisable to travel for appropriate alternative counting on the clinical condition.
• Chronic Malnutrition- the drugs should be avoided or used with extreme caution in patients browsing malnourished, because it may affect the condition adversely.

Based on clinical condition, a private should choose dose adjustment or an appropriate alternative.

Avoid tablet of Combiflam Consumption With Alcohol:

When the drugs interacts with alcohol, it can cause conditions like stomach bleeding, coffee colored or dried blood in stools or cough. If a private consumes alcohol within the course of drugs , it should be reported to a doctor immediately.

Avoid tablet of Combiflam before Lab test:

5-HIAA Urine Test (Moderate): After consuming Combiflam, a private should avoid taking 5-HIAA Urine Test, because it may provides a false-positive result for this test. Thus, it's advisable to share details of all the drugs being consumed and present conditions before undergoing the lab tests.

Combiflam Tablets

Combiflam shouldn't be taken with:

Sometimes, taking quite two medicines at a time can nullify the effect of either medicines or react together to end in some adverse condition which may pose a significant risk to health. it's suggested to read instruction about the compounds and salts available within the medicine and respective results of the interaction. Also, a medical professional should even be conscious of the small print of ongoing medicines, if any, before prescribing combiflam.

Some of the medicines that ought to be avoided while consuming tablet of Combiflam are listed below:

• Methotrexate (Major): Combiflam when taken along side Methotrexate may result within the liver injury, bleeding and breathing problem. The detail of combiflam should be shared with a medical professional beforehand. Dosage should be adjusted supported the need . Also, kidney functions and blood corpuscle count should be monitored closely during the course of the drugs .
• Corticosteroids (Moderate): the mixture of both the medicines can increase the danger of gastrointestinal bleeding. A doctor should be told about consumption of Corticosteroids beforehand. an alternate to Combiflam should be considered after consulting a medical professional.
• Aspirin (Major): Combiflam when taken along side Aspirin may nullify or reduce the effect of Aspirin. aside from that, there's a risk of bleeding. In case, a private experience symptoms like blood in stools, gastrointestinal bleeding and abdominal pain, a doctor should be consulted with none delay because the condition require immediate medical intervention. In such circumstance, an alternate of the drugs should be considered.
• Antihypertensive (Moderate): Combiflam when crazy antihypertensive like Ramipril and Furosemide elevate the danger of kidney damage. In such circumstances, kidney functions should be monitored on the regular basis.

The interaction is typically seen in elderly people. The doses should be adjusted consistent with the clinical condition or an alternate should be selected, if required.

Suspension sort of Combiflam:

• combiflam is out there in suspension form also . It acts as non-steroidal anti-inflammatory drugs.
• The suspension sort of combiflam are often employed by one that is above 6 months.
• The precautions and warnings should remain same in either sort of Combiflam.

Mentioned below is that the list of suspension form which will be used as substitutes of the medicine:

• Adiflam Plus Suspension
• Artigesic 100 mg/162.5 mg Suspension
• Artigesic 100 mg/162.5 mg Suspension
• Bruace Suspension
• Bren Plus 100 mg/162.5 mg Suspension
• Dolomec Suspension
• Ibucon Plus Suspension
• Ibugesic Plus Suspension
• Flexon Suspension
• Imol Suspension
• Ibu P 100 Mg/162.5 Mg Suspension
• Simultin P 100 Mg/162.5 Mg Suspension
• P K 100MG/162.5MG Suspension
• Ibutop 100 Mg/162.5 Mg Suspension
• Ibukind Plus 100 mg/162.5 mg Suspension

Combiflam Variants:

The following are the variants of the medicine:

• Combiflam tablet
• Combiflam syrup
• Combiflam gel
• Combiflam pain relief spray

FAQs

1) How long i want to attend to ascertain the consequences of Combiflam tablet?

Ans: Combiflam tablet starts showing its effect within half-hour of consumption.

2) what's the duration of the effect of Combiflam?

Ans: Combiflam shows its effect till 6 hours from the consumption.

3) Is Combiflam safe to use during pregnancy?

Ans: the utilization of Combiflam tablet isn't recommended for pregnant women unless considerably necessary. All the risks and benefits should be shared with the medical professional beforehand.

4) Is Combiflam tablet, safe to use while breastfeeding?

Ans: Combiflam tablet isn't recommended for breastfeeding women, if not necessary. The related risks and benefits should be discussed beforehand to avoid any longer complications.

5) Is it safe to drive after consuming Combiflam?

Ans: Combiflam can make an individual feel dizzy, sleepy or drowsy. Thus, it's suggested not drive after the consumption of Combiflam.

6) What if I consume an expired Combiflam?

Ans: one dose of expired Combiflam won't produce any adverse effect on health. However, it's recommended to consult a medical professional to get on safe side.

7) what is going to be the consequence of an overdose of Combiflam tablet?

Ans: within the case of an overdose of Combiflam tablet, a private should immediately consult a doctor .

8) Is Combiflam addictive?

Ans: No, Combiflam Tablet isn't addictive.

9) Is there any food item to be avoided while consuming Combiflam tablet?

Ans: No, there's no specific list of food items to be avoided while consumption of Combiflam Tablet.

10) the way to store Combiflam Tablet?

Ans: The Combiflam tablet should be stored at 25°c and will be kept faraway from heat and lightweight .

11) what's Combiflam Tablet wont to treat?

Ans: Combiflam tablet is prescribed for following medical conditions:

• Pain
• Fever
• Cold
• Dental abscess
• Headache
• Muscle pain
• Joint pain

12) What are the side effects of Combiflam Tablet?

Ans: Side effects of Combiflam tablet vary from one individual to a different , and are hooked in to various factors like ongoing drugs, clinical condition, lifestyle, etc. a number of the commonly reported side effects include the following:

• Nausea
• Vomiting
• Fatigue
• Abdominal pain
• Mouth ulcers
• Sever heartburn

13) What precautions should I follow while taking Combiflam?

Ans: Before taking Combiflam, keep the subsequent things in mind:

• Kidney: Patients affected by renal disorder should use this medicine with caution. Dose adjustments would be needed. future use of this medicine may harm the kidney function.
• Liver disease: Patients affected by disease should use this medicine with care. Dose adjustments would be needed.
• Pregnancy: Combiflam are often harmful during pregnancy. One should only take this medicine after consulting the doctor.
• Alcohol: One should avoid taking the suspension sort of the drugs because it may cause extreme drowsiness and increase the danger of liver damage.
• Food: don't take this medicine on an empty stomach because it may cause lose motions.

14) What other information I should know regarding Combiflam?

Ans: Keep all the appointments together with your doctor and therefore the laboratory. The doctor may order certain lab tests to see how your body is responding to Combiflam. If your symptoms aren't yet cured, then speak to your doctor immediately during this regard.

Do not let anyone else take the drugs . aside from this, always keep an inventory of prescription and non-prescription medicines you're taking and other products like vitamins, minerals and other supplements.

15) Is it safe to require Combiflam on an empty stomach?

Ans: Medicines like Ibuprofen, Combiflam and other NSAIDs can cause irritation within the stomach lining. Therefore, it's always suggested to require it along side food or milk.

16) am i able to stop using Combiflam when the pain is relieved?

Ans: Use Combiflam as told by the doctor. If your symptoms are cured then you'll stop this medicine, but only under medical supervision.

17) In what conditions the drugs shouldn't be used?

Ans: Combiflam shouldn't be utilized in the subsequent situations:

• Allergy: If you're allergic to Combiflam or the other NSAID drug, then don't use Combiflam.
• Asthma: If you had a history of asthma, rhinitis and uticaria, then avoid taking the Combiflam.
• Coronary Artery Bypass Surgery (CABG): If you had a recent operation , therefore it's not advised to use Combiflam Tablet.
• Gastro-intestinal bleeding: Patients affected by peptic ulceration and the other food poisoning shouldn't use Combiflam Tablet.

18) Is Combiflam safe for children?

Ans: Combiflam contains ibuprofen that has been used from an extended time now. Infants falling within the weight bracket, shouldn't be recommended with Combiflam. While, the older children won't face issue if they take the Combiflam adhering to the dosage.

19) How and when to offer Combiflam?

Ans: Combiflam should tend along side food and will be strictly taken as per the prescription. One should avoid taking alcohol along side the Combiflam.

20) What are the overall warnings associated with Combiflam?

Ans: Patients should take extreme care if they're affected by following the subsequent medical conditions:

• Malnutrition: the danger of great side effects can't be avoided. supported the physical examination, appropriate adjustments in dosage and prescription of another medicine are often provided by the doctor.
• Gastro-intestinal bleeding: future use of the Combiflam may trigger gastrointestinal bleeding and perforation, especially among elderly and people with such issues. Dosage adjustments could also be required in such cases.
• Alcohol: If an individual is hooked in to alcohol, there are chances of liver damage. In such cases, avoid Combiflam.
• Anaemia: An anaemic should used Combiflam with caution because it may harm an individual’s health. In extreme cases, an alternate medicine should be used.
• Liver impairment: If a patient is affected by liver impairment and other disease, he or she should take care . an in depth watch on liver function and Combiflam dosages could also be advised.

21) What should i do know about the dosage of Combiflam?

Ans: The dosage of the Combiflam is predicated on the subsequent factors:

• Body weight and age of the patient.
• Health condition of the patient
• Severity of the difficulty .
• History of drug reactions and allergies.

Based on the above dosage of the tablet:

Adults: Maximum 4 gms daily dosage of 0.5-1gm to 4-6 hours is required.

Children

• Upto 1 year: 60-120 mg 4-6 hours daily maximum of 4 doses during a day.
• 1-5 years: 120-250mg 4-6 hours maximum of 4 doses during a day.
• 6-12 years: 250-500mg 4-6 hours maximum of 4 doses during a day.

22) How does Combiflam Tablet works?

Ans: The Combiflam works by performing on the brain that triggers pain and risen blood heat .

• It restricts the consequences of enzymes called cyclo-oxygenase (COX).
• The enzymes help the body in producing prostaglandins which are liable for causing pain and redness at the location of injury within the body.
• Reduction of COX enzymes leads to the lower production of prostaglandins.
• Since production of prostaglandins is restricted, it eases the pain and increases blood flow across the skin that causes heat loss sweating.